NEET UG 2025: As the NEET exam draws closer, aspirants across the country are intensifying their preparation strategies, particularly in Biology, where Human Physiology forms a major scoring section. To help students gear up for high-level performance, we’ve compiled a list of 25 multiple-choice questions (MCQs) from Human Physiology — each designed to test deep conceptual understanding and application.
25 MCQs on Human Physiology for NEET UG 2025
1. The oxygen dissociation curve shifts to the right when:
(a) pH increases
(b) CO₂ concentration decreases
(c) Temperature decreases
(d) 2,3-BPG concentration increases
2. Juxtaglomerular cells secrete renin in response to:
(a) Increased glomerular filtration rate
(b) Increased blood pressure
(c) Low blood sodium and pressure
(d) High aldosterone levels
3. The contraction of cardiac muscle is initiated by:
(a) AV node
(b) SA node
(c) Purkinje fibers
(d) Bundle of His
4. Maximum absorption of water occurs in:
(a) Jejunum
(b) Ileum
(c) Large intestine
(d) Stomach
5. Which hormone has both insulin-like and growth-promoting effects?
(a) Thyroxine
(b) GH
(c) Glucagon
(d) Somatomedin
6. The hormone responsible for ovulation is:
(a) LH
(b) FSH
(c) Estrogen
(d) Progesterone
7. Which part of the nephron is impermeable to water?
(a) Proximal convoluted tubule
(b) Descending limb of loop of Henle
(c) Ascending limb of loop of Henle
(d) Collecting duct
8. The pacemaker potential is generated due to:
(a) Na⁺ influx
(b) K⁺ efflux
(c) Cl⁻ influx
(d) Ca²⁺ influx
9. During inspiration, the intrapulmonary pressure:
(a) Increases
(b) Decreases
(c) Remains unchanged
(d) Becomes equal to atmospheric pressure
10. The site of complete digestion of carbohydrates is:
(a) Stomach
(b) Duodenum
(c) Jejunum
(d) Large intestine
11. Which organ is responsible for urea synthesis?
(a) Kidney
(b) Liver
(c) Lungs
(d) Pancreas
12. A decrease in the number of RBCs leads to:
(a) Increase in blood viscosity
(b) Increase in oxygen-carrying capacity
(c) Increase in CO₂ transport
(d) Decreased oxygen transport
13. Which mineral is essential for insulin function?
(a) Iron
(b) Magnesium
(c) Zinc
(d) Calcium
14. The Bohr effect relates to:
(a) Binding of CO₂ to hemoglobin
(b) Unloading of O₂ due to increased CO₂
(c) Shift of oxygen curve to left
(d) CO binding to hemoglobin
15. In a neuron, saltatory conduction occurs due to:
(a) Synapses
(b) Myelin sheath
(c) Axon hillock
(d) Dendrites
16. Cholecystokinin stimulates:
(a) Pancreatic enzyme secretion
(b) Insulin release
(c) Salivary secretion
(d) Gastric acid secretion
17. Which enzyme is absent in gastric juice?
(a) Pepsin
(b) Rennin
(c) Trypsin
(d) Gastric lipase
18. The functional unit of the skeletal muscle is:
(a) Sarcoplasm
(b) Myofibril
(c) Sarcomere
(d) Actin
19. Which hormone increases the reabsorption of Na⁺ in the kidney?
(a) Aldosterone
(b) ADH
(c) ANF
(d) Cortisol
20. The major cation of intracellular fluid is:
(a) Sodium
(b) Potassium
(c) Calcium
(d) Magnesium
21. Which of the following is an example of positive feedback?
(a) Thermoregulation
(b) Regulation of blood pressure
(c) Childbirth contractions
(d) Control of blood glucose
22. Which type of muscle does not fatigue easily and contracts involuntarily?
(a) Cardiac muscle
(b) Skeletal muscle
(c) Smooth muscle
(d) Striated voluntary muscle
23. The majority of CO₂ in blood is transported as:
(a) Bicarbonate ions
(b) Carbaminohemoglobin
(c) Dissolved in plasma
(d) Bound to plasma proteins
24. ADH acts on:
(a) Glomerulus
(b) PCT
(c) Loop of Henle
(d) Collecting duct
25. The enzyme carbonic anhydrase is present in:
(a) Plasma
(b) RBCs
(c) WBCs
(d) Platelets
✅ Answer Key:
1.(d), 2.(c), 3.(b), 4.(c), 5.(d) 6.(a), 7.(c), 8.(a), 9.(b), 10.(c) 11.(b), 12.(d), 13.(c), 14.(b), 15.(b) 16.(a), 17.(c), 18.(c), 19.(a), 20.(b)21.(c), 22.(a), 23.(a), 24.(d), 25.(b)
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These 25 MCQs are not just a test of memory but a simulation of NEET-level thinking. Students who regularly challenge themselves with such questions stand a greater chance of cracking competitive sections and securing top ranks.